Red cell alloimmunization in repeatedly transfused children with beta thalassemia major
نویسندگان
چکیده
منابع مشابه
Red cell alloimmunization in repeatedly transfused patients
INTRODUCTION Repeated blood transfusions can result in the production of alloantibodies against one or more red cell antigens, which complicates subsequent transfusions. Aims: The study was done to find incidence of various red cell alloantibodies; to determine the type of alloantibody; to identify the factors such as frequency of transfusion, splenectomy status, donor ethnicity and gender and ...
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Background: Transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. Alloimmunization is an unwanted side effect of blood transfusion. The present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in Southwest Iran. Patients and Methods: This was a cross-...
متن کاملFrequency and Risk Factors of Red Blood Cell Alloimmunization in Thalassemia Major Patients in Markazi province
Background: Thalassemia is one of the most common genetic disorders throughout the world. Blood transfusion plays an important role in the treatment of thalassemia but it leads to numerous complications such as iron overload and alloimmunization. This study evaluated the frequency and risk factors associated with alloimmunization in thalassemia major patients living in Markazi province, Iran. ...
متن کاملRed Blood Cells Alloimmunization and Autoimmunization in Multi-transfused Thalassemia Patients in South of Iran
Background: Recurrent blood transfusion is a common treatment in patients with thalassemia. The development of antibodies against red blood cell (RBC) antigens complicates RBC cross-matching, enhances the in vivo destruction of transfused cells, accelerates tissue iron overloading, delays the provision of safe transfusion, and reduces health-related quality of life. Materials and Methods: In t...
متن کاملPredicting Factors of Atherosclerosis in Children with Beta-Thalassemia Major
Background: Atherosclerosis is an important cardiovascular disorder in beta-thalassemia major patients. The present study aimed to predict factors of atherosclerosis in children with beta-thalassemia major. Materials and Methods: This cross-sectional study was conducted on 36 patients with beta-thalassemia major and 36 healthy children as the control group. The carotid intima-media thickness ...
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ژورنال
عنوان ژورنال: International Journal of Contemporary Pediatrics
سال: 2017
ISSN: 2349-3291,2349-3283
DOI: 10.18203/2349-3291.ijcp20171486